Abstract

In summary, the described cases were quite characteristic of the classic clinical picture and course of idiopathic retroperitoneal fibrosis (IRPF). The initial symptoms of the disease are mostly non-specific, and the time to reach the diagnosis was slightly longer than described in the literature. The first suspicion usually arises during a radiological examination. Biopsy is not diagnostically necessary, but as described in the cases it is indispensable in ruling out malignancy. GCS treatment is effective in the inflammatory phase of the disease, but due to the progressive course of the disease, it can require regular monitoring and treatment escalation.