Abstract

According to the modern approach, Parkinson’s disease (PD) is a systemic disease, which is accompanied by changes in peripheral nerves and extraneuronal tissues. Non-motor
symptoms can also manifest in the skin, and precede the manifestation of motor symptoms. Polyneuropathy is common among patients with PD, and several skin problems such as dyshidrosis and seborrheic dermatitis are also associated with the disease. These disorders can have a significant impact on the progression of the disease and the patient’s well-being, which is why it is necessary to notice and, if possible, treat them. Patients with Parkinson’s disease have also been found to have a higher than average risk of developing melanoma, as PD and melanoma share several common risk.