Abstract

Vasculitis is a heterogeneous group of disorders associated with systemic autoimmune processes. This article presents a complex case characterized by a prolonged diagnostic journey, highlighting the diagnostic challenges of polyarteritis nodosa. The initial
evaluation focused primarily on a suspected infection. However, the emergence of neurological symptoms pointed toward a systemic condition. Suspicions of vasculitic neuropathy during the diagnostic and therapeutic process necessitated a multidisciplinary approach involving internal medicine, neurology, rheumatology, pathology, and surgery. Multidisciplinary collaboration, comprehensive diagnostics, and the histopathological examination of nerve and muscle tissue were essential in establishing the final diagnosis and initiating appropriate
treatment. Clinical improvement was achieved with immunosuppressive therapy, underscoring the importance of timely and systematic management in the diagnosis and treatment of rare vasculitis.