{"id":4998,"date":"2015-06-18T10:50:30","date_gmt":"2015-06-18T08:50:30","guid":{"rendered":"http:\/\/eestiarst.dbweb.ee\/?p=4998"},"modified":"2015-06-18T10:50:48","modified_gmt":"2015-06-18T08:50:48","slug":"modic-changes-in-spine","status":"publish","type":"post","link":"https:\/\/eestiarst.ee\/en\/modic-changes-in-spine\/","title":{"rendered":"Modic changes in spine"},"content":{"rendered":"<p>Modic changes (MC) are bone marrow and endplate lesions visible on magnetic resonance imaging (MRI) in spinal degenerative diseases and strongly linked with low back pain.<\/p>\n<p>MC type I represents a hypointense signal in T1-weighted imaging (T1WI) and a hyperintense signal in T2-weighted imaging (T2WI), corresponding to vertebral body oedema and hyper-vascularity, MC type II represents a hyperintense signal in both T1WI and T2WI, reflecting fatty replacements of the red bone marrow, and MC type III represents a hypointense signal in T1WI and T2WI, consisting of subchondral bone sclerosis.<\/p>\n<p>How the present knowledge of MC affects the management of spinal degenerative diseases remains unclear. Further studies of MC will explore therapeutic possibilities for future treatments of spinal degenerative diseases.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Modic changes (MC) are bone marrow and endplate lesions visible on magnetic resonance imaging (MRI) in spinal degenerative diseases and strongly linked with low back pain. MC type I represents a hypointense signal in T1-weighted imaging (T1WI) and a hyperintense signal in T2-weighted imaging (T2WI), corresponding to vertebral body oedema and hyper-vascularity, MC type II &#8230;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[1538],"class_list":["post-4998","post","type-post","status-publish","format-standard","hentry","category-articles","tag-review","authors-dagmar-loorits-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/4998","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/comments?post=4998"}],"version-history":[{"count":2,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/4998\/revisions"}],"predecessor-version":[{"id":5000,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/4998\/revisions\/5000"}],"wp:attachment":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/media?parent=4998"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/categories?post=4998"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/tags?post=4998"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}