Backround. <\/b>Omega-3 fatty acids, such as those present in fish oil, have been reported to prolong life in survivors of myocardial infarction. Recent prospective evidence shows that 1 mmol\/l increase in plasma triglyceride concentration increases cardiovascular risk in men 30% and in women up to 76%.<\/p>\n
Experimental and pharmacological studies have shown that omega-3 fatty acids reduce serum triglyceride levels in a dose-dependent manner. The primary mechanisms involve suppression of hepatic very low density lipoprotein and triglyceride production.<\/p>\n
The aim of the study <\/b>was to examine the triglyceride lowering effect of Bio-Marin Natural (Pharma Nord), a concentrate of omega-3, over eight weeks in patients with combined dyslipidaemia without coronary artery disease who are not receiving statin therapy.<\/b><\/p>\n
Material and methods. <\/b>Fifteen patients with fasting hypertriglyceridaemia \u2265 2.0 mmol\/l were given 1. 2 g omega-3 for 8 weeks. The fasting lipid profile was analysed before and after the 8-week study period. Average age was 54 years and mean BMI was 29 kg\/m2.<\/sup><\/p>\n Results. <\/b>As a result, 4 capsules of Bio-Marin Natural per day lowered serum triglycerides significantly, by 27,.4 % (p <0.001) and did not have any effect on the other lipid parameters. Interestingly, the effect of the same dose of omega-3 on lowering triglycerides differed largely and up to 60%.<\/p>\n Conclusion. <\/b>Thus, 1.2 g of omega-3 per day significantly lowered serum triglycerides up to 60% over 8 weeks in patients with combined hyperlipidaemia.<\/p>\n","protected":false},"excerpt":{"rendered":" Backround. Omega-3 fatty acids, such as those present in fish oil, have been reported to prolong life in survivors of myocardial infarction. Recent prospective evidence shows that 1 mmol\/l increase in plasma triglyceride concentration increases cardiovascular risk in men 30% and in women up to 76%. Experimental and pharmacological studies have shown that omega-3 fatty …<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[1540],"class_list":["post-6229","post","type-post","status-publish","format-standard","hentry","category-articles","tag-research","authors-anu-hedman-en","authors-arvo-mesikepp-en","authors-rein-vahisalu-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/6229","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/comments?post=6229"}],"version-history":[{"count":1,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/6229\/revisions"}],"predecessor-version":[{"id":6230,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/6229\/revisions\/6230"}],"wp:attachment":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/media?parent=6229"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/categories?post=6229"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/tags?post=6229"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}