Our objective was to evaluate the importance and susceptibility pattern of A. baumannii, P. aeruginosa, and K. pneumoniae in Estonian ICUs. From April to December 2003, a total of 128 A. baumannii, 99 P. aeruginosa, and 98 K. pneumoniae strains were collected from North-Estonian Regional Hospital, Tartu University Clinics, East Tallinn Central Hospital, and Narva Hospital. To clear up methodological discrepancies, the data of E-test and disk-diffusion method were compared.<\/p>\n
Of the A. baumannii strains 60% were sensitive to to ampicillin\/sulbactam and to cefepime, 95% were sensitive to meropenem and imipenem, and 75% to amikacin. Of the P. aeruginosa strains 79% were sensitive to piperacillin\/tazobactam, 58% to ceftazidime, 81% to meropenem, 72% to imipenem, 69% to ciprofloxacin and 97% to amikacin. The susceptibility of the K. pneumoniae isolates to meropenem and imipenem was 99%, to ciprofloxacin 91% and to amikacin 98%. In all 4 ICUs, sensitivity among the K. pneumoniae strains was similar, whereas in local discrepancies occurred the susceptibility pattern of A. baumannii and P. aeruginosa. The discordance between E-test and disk-diffusion was pathogen-specific. In the case of K. pneumoniae, less errors were found, while in the case of A. baumannii and P. aeruginosa, E-tests are recommended for susceptibility testing. Most active agents against gram-negative pathogens were carbapenems and amikacin. For empirical treatment, meropenem and imipenem are preferred due to their high activity and the lowest MIC values.<\/p>\n","protected":false},"excerpt":{"rendered":"
Our objective was to evaluate the importance and susceptibility pattern of A. baumannii, P. aeruginosa, and K. pneumoniae in Estonian ICUs. From April to December 2003, a total of 128 A. baumannii, 99 P. aeruginosa, and 98 K. pneumoniae strains were collected from North-Estonian Regional Hospital, Tartu University Clinics, East Tallinn Central Hospital, and Narva …<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[1540],"class_list":["post-6409","post","type-post","status-publish","format-standard","hentry","category-articles","tag-research","authors-aino-room-en","authors-argo-parts-en","authors-epp-sepp-en","authors-helle-magi-en","authors-karin-otter-en","authors-krista-loivukene-en","authors-paul-naaber-en","authors-ulle-kallandi-en","authors-vivika-adamson-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/6409","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/comments?post=6409"}],"version-history":[{"count":1,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/6409\/revisions"}],"predecessor-version":[{"id":6410,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/6409\/revisions\/6410"}],"wp:attachment":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/media?parent=6409"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/categories?post=6409"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/tags?post=6409"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}