Periodontitis is a chronic infectious disease which leads to the destruction of the gingiva<\/p>\n
and alveolar bone until tooth loss. The evidence of bacterial specification in periodontitis<\/p>\n
patients has led to periodontal instrumentation combined with systemic antibiotic<\/p>\n
treatment. The main objectives of the study were 1) to evaluate the efficacy of<\/p>\n
instrumentation according to the presence of pathogens, 2) to determine the spectrum of<\/p>\n
pathogens and 3) to compare the total degree of colonisation with the number of the<\/p>\n
pathogens.<\/p>\n
Altogether 140 patients aged 13\u201368 years were studied. Samples from the<\/p>\n
periodontal pockets were placed in anaerobic transport vials; five-fold dilutions were<\/p>\n
made and seeded onto the Brucella and BVTS agar plates. The pathogens were identified<\/p>\n
according to their colonial and cellular morphology, the potency disk pattern and the<\/p>\n
biochemical profiles.<\/p>\n
After periodontal instrumentation no pathogens were isolated in 46 patients,<\/p>\n
94 were colonised with 1\u20135 pathogenic species. Fifty-three patients harboured one<\/p>\n
pathogen, 27 harboured two, 12 three and two patients harboured 5 pathogens. The total<\/p>\n
load of colonisation varied from 0 to 8.4 CFU\/mL (median 5.5 CFU\/mL), being<\/p>\n
positively correlated with the number of isolated pathogens (p<0.001). The P.<\/p>\n
intermedia\/nigrescens group was present in 37, A. actinomycetemcomitans in 36 P.<\/p>\n
micros in 12, P. gingivalis in 7, B. forsythus in 4 and C. rectus in 2 patients. Higher<\/p>\n
colonisation with oral bacteria indicates presence of periodontal pathogens. Of these<\/p>\n
patients 33% remained pathogen-free, indicating the success of primary mechanical<\/p>\n
therapy. However, 67% of the patients were also colonised with one to five different<\/p>\n
pathogens. Therefore, for the successful diagnosis and therapy of periodontal diseases,<\/p>\n
individual microbiological examination of each patient is recommended.<\/p>\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
Periodontitis is a chronic infectious disease which leads to the destruction of the gingiva and alveolar bone until tooth loss. The evidence of bacterial specification in periodontitis patients has led to periodontal instrumentation combined with systemic antibiotic treatment. The main objectives of the study were 1) to evaluate the efficacy of instrumentation according to the …<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[1538],"class_list":["post-6556","post","type-post","status-publish","format-standard","hentry","category-articles","tag-review","authors-ene-renate-pahkla-en","authors-mare-saag-en","authors-paul-naaber-en","authors-taive-koppel-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/6556","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/comments?post=6556"}],"version-history":[{"count":1,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/6556\/revisions"}],"predecessor-version":[{"id":6557,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/posts\/6556\/revisions\/6557"}],"wp:attachment":[{"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/media?parent=6556"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/categories?post=6556"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/eestiarst.ee\/en\/wp-json\/wp\/v2\/tags?post=6556"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}