Symptoms of acute HIV-infection usually appear 2-4 weeks after infection in 40-90% of patients. The symptoms are non-specific, but nonetheless it is important to suspect the infection and to test the patients for HIV. Early detection and immediate antiretroviral treatment (ART) enable to avoid development of immunodeficiency and related diseases. In addition, ART reduces the risk of cardiovascular diseases and renal impairment caused by immune activation. It is extremely important to emphasize treatment as prevention: a HIV positive patient on ART with viral suppression is not infectious (undetectable = untransmittable, U=U). This case report describes a case of a 42-year-old man who was diagnosed with HIV at an early stage, but the diagnosis was made after multiple visits to different medical facilities and doctors.