REVIEW – April 2020

Late complicaions of the treatment of childhood malignant tumours

Authors: Laura Johanna Mettis

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Abstract

Remarkable improvements have been made in the treatment of childhood cancer with the overall 5-year survival rate exceeding 80%. However, survivors of paediatric cancer have worse long-term health outcomes compared to general population. The cumulative incidence and cumulative burden of childhood cancer survivors are the highest for cardiovascular and endocrine systems and the main contributors to early mortality is secondary neoplasm. Childhood cancer survivors should be systematically monitored by interdistsiplinary medical teams for early recognition and timely management of läte effects of cancer treatment.