Abstract

COVID-19 pandemic is caused by SARS-CoV-2 virus – a respiratory infection, which can produce also systemic, e.g. thrombotic, complications. Prevalence of venous and arterial thrombosis is higher in patients with COVID-19 compared to the rest of population. Inflammation (i.e. cytokine storm) results in endothelial damage that activates coagulation cascade. Endothelial dysfunction combined with stasis can lead to thrombotic events. The current overview describes the mechanisms of COVID-19-caused endothelial dysfunction and thrombosis, as well as the prevalence and prevention strategies of thrombosis.