Neuropsychological rehabilitation is aimed at ameliorating cognitive, emotional, behavioural, and psychosocial problems caused by brain injury. Despite the relatively short history, the efficacy of neuropsychological interventions has been proved both on an individual and a national level. The holistic rehabilitation model, in which the patients’ family and environment are closely involved in the rehabilitation process, has become widespread. The process of rehabilitation begins with a thorough assessment and setting of patient-centered goals. After suitable interventions are implemented, support for the generalisation of new skills assumes vital importance. Although the field of neuropsychological rehabilitation is still relatively new in Estonia, opportunities for better training and services are improving fast.