REVIEW – January 2012

Pharmacokinetics and dosage forms in clinical usage of medicines


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The effects of a drug are determined by its concentration on the receptor. The concentration of the drug on the receptor depends on the right choice of dosage form.

Dosage form is the physical form of a dose of a drug or medication intended for administration or consumption. By using the correct dosage form it is possible to ensure the therapeutic effect of the drug, to exert the therapeutic effect at a specific site and to minimize the side-effects of the drug. The oral route continues to be the preferred route for drug administration. There is a continuous development of orally administered dosage forms to achieve a therapeutic effect at a specific location in the gastroinestinal tract or to ensure an effect in the organism. However, during the past decade the systemic administration of drugs by inhalation and transdermal administration has also expanded.